niks

Kochani, zabużenia hormonalne mogą być chyba z każdymi neuroleptykami, a może i nawet z lekami przeciwdepresyjnymi. Ale supiryd działa, w porównianiu do SSRI na tyle szybko, że można go traktować jako pomoc 'doraźną', czyli nie długotrwała, tylko stosować w trudnych okresach. To by było idealnie. Przynajmniej ja chciałbym przyjrzeć się mu w tym kierunku, bo mam nerwicę z powodu współżycia z ludźmi i ciągłe napiecie na tym tle, niepokoje o przyszłość, itd. Zresztą ja się przytycia ani cycków za bardzo nie boję bo wyglądam jak wampir i tak :)

http://learnmem.cshlp.org/content/12/4/399.full Systemic blockade of D2-like dopamine receptors facilitates extinction of conditioned fear in mice Używali sulpirydu. = Sulpiryd może mieć pozytywne działanie na zapominanie lęków! ----------------------------- Tutaj też ciekawy artykół: 'individuals with high prefrontal DRD2/3 availability may be more responsive toward aversive and stressful information. Through this mechanism, dopaminergic neurotransmission might influence vulnerability for affective and anxiety disorders.' Czyli blokowanie DR D2/D3 (Sulpiryd) może pomóc nerwicy/lękach/niepokoju!!! Hum Brain Mapp. 2010 May;31(5):716-26. Human dopamine receptor D2/D3 availability predicts amygdala reactivity to unpleasant stimuli. Kobiella A, Vollstädt-Klein S, Bühler M, Graf C, Buchholz HG, Bernow N, Yakushev IY, Landvogt C, Schreckenberger M, Gründer G, Bartenstein P, Fehr C, Smolka MN. Source Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany. Abstract Dopamine (DA) modulates the response of the amygdala. However, the relation between dopaminergic neurotransmission in striatal and extrastriatal brain regions and amygdala reactivity to affective stimuli has not yet been established. To address this issue, we measured DA D2/D3 receptor (DRD2/3) availability in twenty-eight healthy men (nicotine-dependent smokers and never-smokers) using positron emission tomography with [18F]fallypride. In the same group of participants, amygdala response to unpleasant visual stimuli was determined using blood oxygen level-dependent (BOLD) functional magnetic resonance imaging. The effects of DRD2/3 availability in emotion-related brain regions and nicotine dependence on amygdala response to unpleasant stimuli were examined by multiple regression analysis. We observed enhanced prefrontal DRD2/3 availability in those individuals with higher amygdala response to unpleasant stimuli. As compared to never-smokers, smokers showed an attenuated amygdala BOLD response to unpleasant stimuli. Thus, individuals with high prefrontal DRD2/3 availability may be more responsive toward aversive and stressful information. Through this mechanism, dopaminergic neurotransmission might influence vulnerability for affective and anxiety disorders. Neuronal reactivity to unpleasant stimuli seems to be reduced by smoking. This observation could explain increased smoking rates in individuals with mental disorders. PMID: 19904802 [PubMed - indexed for MEDLINE]